Description

n-(2-Bromo-5-((Hydroxyimino)Methyl)Pyridin-3-Yl)-Pivalamide is a specialized pyridine derivative and a high-purity organic intermediate of significant interest in advanced chemical synthesis. Its core value lies in its unique molecular scaffold, which incorporates both a bromo substituent and a hydroxyiminomethyl functional group, making it a versatile building block for constructing complex heterocyclic systems. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly in medicinal chemistry programs targeting enzyme inhibition.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase or protease enzymes.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides with specific modes of action.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular probes to study biological pathways and protein functions.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis or organocatalysts.
• Material Science Research: A potential monomer or functional additive in the development of advanced polymers or organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	n-(2-Bromo-5-((Hydroxyimino)Methyl)Pyridin-3-Yl)-Pivalamide
CAS No.	1142192-46-8
Molecular Formula	C12H16BrN3O2
Molecular Weight	314.18 g/mol
Synonyms	Pivalamide, N-[2-bromo-5-[(hydroxyimino)methyl]-3-pyridinyl]-; 2-Bromo-5-((hydroxyimino)methyl)pyridin-3-amine pivalamide; 3-Amino-2-bromo-5-pyridinecarboxaldehyde oxime pivalamide; 1142192-46-8; Tert-butylamide of 2-bromo-5-(hydroxyiminomethyl)nicotinic acid
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-5-((Hydroxyimino)Methyl)Pyridin-3-Yl)-Pivalamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.