Description

n-(2-Methoxy-4-(Trimethylsilyl)Pyridin-3-Yl)-Pivalamide is a high-value, organosilicon-functionalized pyridine derivative used as a sophisticated synthetic intermediate. This compound is critical for constructing complex molecular architectures, particularly in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for its unique steric and electronic properties imparted by the trimethylsilyl and pivalamide groups.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Agrochemical Research: Used in developing new generation pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Precursor: Employed in the synthesis of functionalized organic materials and silicon-containing polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	n-(2-Methoxy-4-(Trimethylsilyl)Pyridin-3-Yl)-Pivalamide
CAS No.	1142192-43-5
Molecular Formula	C14H24N2O2Si
Molecular Weight	280.44 g/mol
Synonyms	Pivalamide, N-[2-methoxy-4-(trimethylsilyl)-3-pyridinyl]-; 2-Methoxy-4-(trimethylsilyl)-3-pyridinylpivalamide; 3-Pyridinecarboxamide, N-[2-methoxy-4-(trimethylsilyl)-3-pyridinyl]-2,2-dimethyl-; N-(2-Methoxy-4-(trimethylsilyl)pyridin-3-yl)-2,2-dimethylpropanamide; TMS-Pyridine Pivalamide Derivative; CAS 1142192-43-5
EINECS	Contact for details

Quality Control

Our production of n-(2-Methoxy-4-(Trimethylsilyl)Pyridin-3-Yl)-Pivalamide adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity, typically meeting research-grade and custom synthesis specifications. Quality is verified by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.