Description

n-(3-Hydroxy-2-Iodopyridin-4-Yl)Pivalamide is a specialized iodinated pyridine derivative that serves as a high-value synthetic intermediate. This compound is critical for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides that require a halogenated pyridine core.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function or cellular pathways due to its iodine handle for further functionalization.
• Material Science: Potential intermediate in the synthesis of organic electronic materials or liquid crystals.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects.

Basic Information

Product Name	n-(3-Hydroxy-2-Iodopyridin-4-Yl)Pivalamide
CAS No.	1142192-39-9
Molecular Formula	C10H13IN2O2
Molecular Weight	320.13 g/mol
Synonyms	4-(2,2-Dimethylpropanamido)-2-iodopyridin-3-ol; Pivalamide, N-(3-hydroxy-2-iodo-4-pyridinyl)-; 2-Iodo-3-hydroxy-4-pivalamidopyridine; 4-Pivalamido-2-iodopyridin-3-ol; N-(3-Hydroxy-2-iodopyridin-4-yl)-2,2-dimethylpropanamide
EINECS	Contact for details

Quality Control

Every batch of n-(3-Hydroxy-2-Iodopyridin-4-Yl)Pivalamide is produced and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry to ensure identity, potency, and consistency. A Certificate of Analysis (COA) is supplied with each shipment, and custom purity grades (e.g., >97%, >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.