Description

2-Bromo-5-Iodopyridin-3-Yl tert-Butyl Carbonate is a high-purity, multi-functional pyridine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its dual halogen functionality, which provides versatile reactivity for cross-coupling reactions and further derivatization. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting neurological disorders and oncology.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides, herbicides, and fungicides with enhanced efficacy.
• Material Science Research: Used in the development of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl and heterobiaryl structures.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and tags for studying biological systems and protein interactions.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated pyridine-based ligands for transition metal catalysis.

Basic Information

Product Name	2-Bromo-5-Iodopyridin-3-Yl tert-Butyl Carbonate
CAS No.	1142192-37-7
Molecular Formula	C10H11BrINO3
Molecular Weight	400.01 g/mol
Synonyms	tert-Butyl (2-bromo-5-iodopyridin-3-yl) carbonate; 3-Pyridinol, 2-bromo-5-iodo-, 1,1-dimethylethyl carbonate; 2-Bromo-5-iodopyridin-3-ol tert-butyl carbonate; (2-Bromo-5-iodopyridin-3-yl) tert-butyl carbonate; 2-Bromo-5-iodo-3-pyridyl tert-butyl carbonate; tert-Butyl 2-bromo-5-iodopyridin-3-yl carbonate; BOC-protected 2-bromo-5-iodopyridin-3-ol
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Iodopyridin-3-Yl tert-Butyl Carbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.