Description

tert-Butyl 2-(3-Hydroxyprop-1-ynyl)pyridin-3-yl-carbonate is a specialized pyridine derivative featuring both a protected carbonate and a terminal alkyne with a hydroxyl group, making it a versatile and valuable synthetic intermediate. This compound is engineered for high-precision chemical synthesis, offering controlled reactivity for constructing complex molecular architectures. It is primarily utilized by pharmaceutical and agrochemical research and development teams for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its functional groups for structural diversification.
• Chemical Biology Probes: Serves as a precursor for click chemistry applications, enabling the labeling and study of biomolecules due to its terminal alkyne moiety.
• Material Science Research: Employed in the development of novel organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) services requiring high-purity, advanced intermediates.

Basic Information

Product Name	tert-Butyl 2-(3-Hydroxyprop-1-ynyl)pyridin-3-yl-carbonate
CAS No.	1142192-35-5
Molecular Formula	C13H15NO4
Molecular Weight	249.26 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)oxy]-2-(3-hydroxy-1-propynyl)pyridine; 2-(3-Hydroxyprop-1-yn-1-yl)-3-[[(1,1-dimethylethoxy)carbonyl]oxy]pyridine; tert-Butyl 2-(3-hydroxyprop-1-yn-1-yl)pyridin-3-yl carbonate; 3-Pyridinol, 2-(3-hydroxy-1-propyn-1-yl)-, 1-(1,1-dimethylethyl) ester; Boc-protected hydroxypropynyl pyridine derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(3-Hydroxyprop-1-ynyl)pyridin-3-yl-carbonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.