Description

n-(2-Bromo-5-Hydroxypyridin-3-Yl)Pivalamide is a high-purity, functionalized pyridine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its halogenated pyridine core for bioactivity.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	n-(2-Bromo-5-Hydroxypyridin-3-Yl)Pivalamide
CAS No.	1142192-30-0
Molecular Formula	C10H13BrN2O2
Molecular Weight	273.13 g/mol
Synonyms	2-Bromo-5-hydroxy-N-(2,2-dimethylpropanoyl)pyridin-3-amine; Pivalamide, N-(2-bromo-5-hydroxy-3-pyridinyl)-; 3-Amino-2-bromo-5-hydroxypyridine Pivalamide; 2-Bromo-5-hydroxy-3-pyridinyl-pivalamide; 1142192-30-0; N-(2-Bromo-5-hydroxypyridin-3-yl)-2,2-dimethylpropanamide
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-5-Hydroxypyridin-3-Yl)Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) with batch-specific data are provided to guarantee supply reliability and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.