Description

2-Chloro-3-(Dimethoxymethyl)-4-Iodopyridine is a versatile and highly functionalized pyridine derivative, serving as a critical advanced intermediate in modern synthetic organic chemistry. Its unique halogen and protected aldehyde functionality make it an indispensable building block for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands used in transition metal catalysis for cross-coupling and other key reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-3-(Dimethoxymethyl)-4-Iodopyridine
CAS No.	1142192-28-6
Molecular Formula	C9H11ClINO2
Molecular Weight	327.55 g/mol
Synonyms	4-Iodo-2-chloro-3-(dimethoxymethyl)pyridine; 2-Chloro-4-iodo-3-(dimethoxymethyl)pyridine; 3-(Dimethoxymethyl)-2-chloro-4-iodopyridine; Pyridine, 2-chloro-3-(dimethoxymethyl)-4-iodo-; (2-Chloro-4-iodopyridin-3-yl)dimethoxymethane
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(Dimethoxymethyl)-4-Iodopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to quality supports your R&D and scale-up activities with reliable, high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.