Description

tert-Butyl 2,5-Dibromopyridin-3-Yl Carbonate is a high-purity, protected pyridine derivative designed for advanced synthetic chemistry. This compound serves as a critical versatile building block for the construction of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for researchers and process chemists in the life sciences industry who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex pyridine or heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as those for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The bromine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Functional Group Manipulation: The tert-butyl carbonate (Boc) protecting group allows for selective deprotection and further functionalization at a later synthetic stage.

Basic Information

Product Name	tert-Butyl 2,5-Dibromopyridin-3-Yl Carbonate
CAS No.	1142192-26-4
Molecular Formula	C10H11Br2NO3
Molecular Weight	353.01 g/mol
Synonyms	tert-Butyl carbonic acid 2,5-dibromopyridin-3-yl ester; 3-((tert-Butoxycarbonyl)oxy)-2,5-dibromopyridine; 2,5-Dibromopyridin-3-yl tert-butyl carbonate; 3-Pyridinol, 2,5-dibromo-, 1-(1,1-dimethylethyl) carbonate; Boc-Protected 2,5-Dibromopyridin-3-ol
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,5-Dibromopyridin-3-Yl Carbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.