Description

n-(2-Chloro-6-Hydroxypyridin-3-Yl)Pivalamide is a specialized pyridine derivative that serves as a high-value pharmaceutical intermediate and fine chemical building block. Its molecular structure, featuring both chloro and hydroxypyridine moieties, makes it a critical precursor for synthesizing complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used as a precursor for developing advanced crop protection agents, including herbicides and insecticides.
• Chemical Research & Development: Serves as a versatile reagent for organic synthesis and medicinal chemistry research in academic and industrial laboratories.
• Fine Chemical Production: Employed in the manufacture of other high-purity, specialty chemicals for various industrial applications.
• Ligand and Catalyst Development: Potential use in creating novel ligands for metal catalysis due to its nitrogen and oxygen donor atoms.

Basic Information

Product Name	n-(2-Chloro-6-Hydroxypyridin-3-Yl)Pivalamide
CAS No.	1142192-18-4
Molecular Formula	C10H13ClN2O2
Molecular Weight	228.68 g/mol
Synonyms	2-Chloro-6-hydroxy-N-(2,2-dimethylpropanoyl)pyridin-3-amine; Pivalamide, N-(2-chloro-6-hydroxy-3-pyridinyl)-; 3-Amino-2-chloro-6-hydroxypyridine pivalamide; 2-Chloro-6-hydroxy-3-pyridinyl-pivalamide; N-(2-Chloro-6-hydroxypyridin-3-yl)-2,2-dimethylpropanamide; 1142192-18-4; Tert-butylamide of 2-chloro-6-hydroxynicotinic acid (derivative)
EINECS	Contact for details

Quality Control

Our n-(2-Chloro-6-Hydroxypyridin-3-Yl)Pivalamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.