Description

4-Amino-5-Methoxynicotinonitrile is a high-value pharmaceutical intermediate and versatile building block in organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and other therapeutic areas. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex drug molecules, especially kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its functionalized pyridine core.
• Fine Chemical Production: Serves as a versatile precursor for creating specialty chemicals, dyes, and functional materials.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological pathways.

Basic Information

Product Name	4-Amino-5-Methoxynicotinonitrile
CAS No.	1142192-15-1
Molecular Formula	C7H7N3O
Molecular Weight	149.15 g/mol
Synonyms	5-Methoxy-4-aminonicotinonitrile; 4-Amino-5-methoxypyridine-3-carbonitrile; 3-Cyano-5-methoxypyridin-4-amine; 4-Amino-5-methoxy-3-pyridinecarbonitrile; Nicotinonitrile, 4-amino-5-methoxy-; 5-Methoxy-4-aminopyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Methoxynicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.