Description

3-Allyl-2-Chloro-4-Iodopyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring reactive chlorine, iodine, and allyl groups, makes it an exceptionally versatile building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to introduce key functional groups and create novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis & Scale-Up: An ideal substrate for contract research organizations (CROs) and CDMOs performing custom synthesis and process development.

Basic Information

Product Name	3-Allyl-2-Chloro-4-Iodopyridine
CAS No.	1142192-13-9
Molecular Formula	C8H7ClIN
Molecular Weight	279.50 g/mol
Synonyms	2-Chloro-3-allyl-4-iodopyridine; 4-Iodo-3-allyl-2-chloropyridine; 3-Allyl-2-chloro-4-iodopyridine; Pyridine, 3-allyl-2-chloro-4-iodo-; 2-Chloro-4-iodo-3-(2-propen-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Allyl-2-Chloro-4-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and air. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.