Description

tert-Butyl (6-Chloro-5-Pivalamidopyridin-2-Yl)-Methylcarbamate is a high-purity, advanced pharmaceutical intermediate critical for modern drug synthesis. This compound serves as a key building block in the development of active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is essential for research and manufacturing organizations in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise and reliable synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Bioconjugation & Proteomics Research: Used in the development of chemical probes and linkers for studying biological systems.
• Agrochemical Synthesis: Serves as a building block for creating novel crop protection agents and pesticides.
• Material Science: Employed in the research and development of specialty polymers and advanced organic materials.
• Academic & R&D Laboratories: Utilized in medicinal chemistry programs for hit-to-lead optimization and structure-activity relationship (SAR) studies.
• Contract Manufacturing (CMO/CDMO): Supplied to organizations providing custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	tert-Butyl (6-Chloro-5-Pivalamidopyridin-2-Yl)-Methylcarbamate
CAS No.	1142192-00-4
Molecular Formula	C16H24ClN3O3
Molecular Weight	341.83 g/mol
Synonyms	tert-Butyl N-[(6-chloro-5-pivalamidopyridin-2-yl)methyl]carbamate; 2-Pyridinecarboxamide, 6-chloro-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-5-(2,2-dimethyl-1-oxopropoxy)-; BOC-6-Chloro-5-Pivalamido-2-Picolylamine; 6-Chloro-5-(pivalamido)-2-((tert-butoxycarbonyl)aminomethyl)pyridine; 1142192-00-4; tert-Butyl ((6-chloro-5-(pivalamido)pyridin-2-yl)methyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl (6-Chloro-5-Pivalamidopyridin-2-Yl)-Methylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing full specifications and confirming compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.