Description

n-(6-((tert-Butyldimethylsilyloxy)Methyl)-2-Chloropyridin-3-Yl)Pivalamide is a high-value, organosilicon-protected pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a protected hydroxyl group and a reactive chloropyridine scaffold, enabling precise and complex molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where controlled functionalization is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Chemical Research & Development: Serves as a versatile precursor for creating complex heterocyclic compounds and functionalized ligands.
• Material Science: Potential intermediate for synthesizing specialty polymers or organic electronic materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring protected functional groups and specific regiochemistry.

Basic Information

Product Name	n-(6-((tert-Butyldimethylsilyloxy)Methyl)-2-Chloropyridin-3-Yl)Pivalamide
CAS No.	1142191-94-3
Molecular Formula	C17H29ClN2O2Si
Molecular Weight	356.96 g/mol
Synonyms	2-Chloro-N-[6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-3-pyridinyl]-2,2-dimethylpropanamide; Pivalamide, N-[6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-chloro-3-pyridinyl]-; 2-Chloro-N-(6-(((tert-butyldimethylsilyl)oxy)methyl)pyridin-3-yl)pivalamide; TBDMS-protected Chloropyridine Pivalamide; 1142191-94-3; tert-Butyldimethyl((5-(pivalamido)-6-chloropyridin-2-yl)methoxy)silane
EINECS	Contact for details

Quality Control

Our n-(6-((tert-Butyldimethylsilyloxy)Methyl)-2-Chloropyridin-3-Yl)Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Incompatible with strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.