Description

n-(2-Chloro-6-(Hydroxymethyl)Pyridin-3-Yl)-Pivalamide is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine-based structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture is required for efficacy and safety. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its bioactive pyridine core.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final steps of API production for targeted therapies.
• Bioconjugation & Probe Development: Utilized in creating labeled compounds for diagnostic and biochemical research applications.

Basic Information

Item	Details
Product Name	n-(2-Chloro-6-(Hydroxymethyl)Pyridin-3-Yl)-Pivalamide
CAS No.	1142191-92-1
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.70 g/mol
Synonyms	2-Chloro-6-(hydroxymethyl)-N-(2,2-dimethylpropanoyl)pyridin-3-amine; Pivalamide, N-[2-chloro-6-(hydroxymethyl)-3-pyridinyl]-; 1142191-92-1; 3-Amino-2-chloro-6-(hydroxymethyl)pyridine pivalamide; N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)-2,2-dimethylpropanamide
EINECS	Contact for details

Quality Control

Our n-(2-Chloro-6-(Hydroxymethyl)Pyridin-3-Yl)-Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.