Description

6-Chloro-5-Pivalamidopicolinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific picolinic acid and amide functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, especially protease inhibitors and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides and pesticides with targeted modes of action.
• Chemical Synthesis: Serves as a versatile precursor for creating novel heterocyclic compounds and fine chemicals.
• Bioconjugation & Probe Development: Utilized in medicinal chemistry for creating labeled compounds and biochemical probes.
• Academic & Industrial R&D: Essential material for method development and exploratory research in organic and medicinal chemistry.

Basic Information

Product Name	6-Chloro-5-Pivalamidopicolinic Acid
CAS No.	1142191-83-0
Molecular Formula	C11H13ClN2O3
Molecular Weight	256.69 g/mol
Synonyms	5-[(2,2-Dimethylpropanoyl)amino]-6-chloropyridine-2-carboxylic Acid; 6-Chloro-5-pivalamidopyridine-2-carboxylic Acid; 6-Chloro-5-(pivalamido)picolinic Acid; 2-Pyridinecarboxylic acid, 6-chloro-5-[(2,2-dimethyl-1-oxopropyl)amino]-; 6-Chloro-5-(2,2-dimethylpropanamido)picolinic Acid; Picolinic acid, 6-chloro-5-pivalamido-; 1142191-83-0
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Pivalamidopicolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.