Description

3-Allyl-6-Bromo-2-Chloropyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring bromine, chlorine, and an allyl group, makes it a versatile intermediate for constructing complex molecules through cross-coupling and functional group transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings due to the reactive bromine and chlorine substituents, enabling rapid diversification of molecular libraries.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring precise halogenated intermediates.

Basic Information

Product Name	3-Allyl-6-Bromo-2-Chloropyridine
CAS No.	1142191-82-9
Molecular Formula	C8H7BrClN
Molecular Weight	232.50 g/mol
Synonyms	6-Bromo-2-chloro-3-(2-propen-1-yl)pyridine; 2-Chloro-6-bromo-3-allylpyridine; 3-Allyl-2-chloro-6-bromopyridine; Pyridine, 3-allyl-6-bromo-2-chloro-; 1142191-82-9; Allyl bromochloropyridine derivative; Bromochloropyridine intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-Allyl-6-Bromo-2-Chloropyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain optimal purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.