Description

1-(5-Bromo-3-Fluoropyridin-2-Yl)Piperazine is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated pyridine-piperazine structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in the areas of central nervous system (CNS) and oncology treatments.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule drug candidates.
• Agrochemical Research: Used in the synthesis of experimental compounds for crop protection and pesticide development.
• Chemical Biology Probes: Serves as a versatile scaffold for creating molecular probes to study biological pathways and protein interactions.
• Material Science: Potential precursor for the synthesis of specialized ligands and functionalized polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic & Industrial R&D: Fundamental research reagent in universities and corporate labs for heterocyclic chemistry exploration.

Basic Information

Product Name	1-(5-Bromo-3-Fluoropyridin-2-Yl)Piperazine
CAS No.	1141669-85-3
Molecular Formula	C9H11BrFN3
Molecular Weight	260.11 g/mol
Synonyms	5-Bromo-3-fluoro-2-piperazin-1-ylpyridine; 2-(Piperazin-1-yl)-5-bromo-3-fluoropyridine; 1-(5-Bromo-3-fluoropyridin-2-yl)piperazine; 5-Bromo-3-fluoro-2-(1-piperazinyl)pyridine; 1141669-85-3; 5-Bromo-3-fluoro-2-piperazin-1-yl-pyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-3-Fluoropyridin-2-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.