Description

Ethyl (1S,2R)-2-(4-Fluorobenzylamino)Cyclopentanecarboxylate is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its value lies in its defined stereochemistry, which is critical for the development of enantiomerically pure active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds where the (1S,2R) configuration is required for biological activity.
• Process Chemistry: Serves as a critical intermediate in scale-up and process optimization for API manufacturing under GMP conditions.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development.
• Custom Synthesis: A starting point for the custom synthesis of more complex, fluorinated chiral molecules.

Basic Information

Product Name	Ethyl (1S,2R)-2-(4-Fluorobenzylamino)Cyclopentanecarboxylate
CAS No.	1140972-21-9
Molecular Formula	C15H20FNO2
Molecular Weight	265.33 g/mol
Synonyms	(1S,2R)-Ethyl 2-[(4-Fluorophenyl)methylamino]cyclopentanecarboxylate; Ethyl (1S,2R)-2-[(4-Fluorobenzyl)amino]cyclopentanecarboxylate; (1S,2R)-2-[(4-Fluorobenzyl)amino]cyclopentanecarboxylic Acid Ethyl Ester; 1140972-21-9; UNII-9J8F0C8V4I; 9J8F0C8V4I; SCHEMBL21824027; AKOS040759232.
EINECS	Contact for details

Quality Control

Our Ethyl (1S,2R)-2-(4-Fluorobenzylamino)Cyclopentanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.