Description

2-Bromo-6,7-Dihydro-5H-Cyclopenta[B]Pyridine is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of new active ingredients for crop protection products, leveraging its fused bicyclic structure.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of organic electronic materials and advanced polymers where its bromine moiety allows for further functionalization.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, complex heterocyclic cores.

Basic Information

Product Name	2-Bromo-6,7-Dihydro-5H-Cyclopenta[B]Pyridine
CAS No.	1140240-18-1
Molecular Formula	C8H8BrN
Molecular Weight	198.06 g/mol
Synonyms	2-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridine; 2-Bromocyclopentapyridine; 6,7-Dihydro-5H-cyclopenta[b]pyridin-2-yl bromide; 2-Bromo-5,6,7,8-tetrahydroquinoline (incorrect but common misnomer); 2-Bromo-6,7-dihydrocyclopenta[b]pyridine; CPB-Br; Bromo-CPP
EINECS	Contact for details

Quality Control

Our 2-Bromo-6,7-Dihydro-5H-Cyclopenta[B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.