Description

6,8-Difluoro-4-Pyridin-3-Yl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline is a high-value, multi-cyclic heteroaromatic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its complex fused-ring structure, featuring both pyridine and quinoline moieties with strategic fluorine substitutions, makes it an essential building block for creating novel molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of new active ingredients targeting a range of biological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its fluorinated quinoline core for enhanced bioactivity and environmental stability.
• Material Science Precursor: Serves as a sophisticated organic ligand or building block for advanced organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probe: Utilized in academic and industrial research to create molecular probes for studying enzyme function and protein interactions.
• Catalyst & Ligand Development: Acts as a scaffold for designing novel asymmetric catalysts and complexing agents in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client-specific projects.

Basic Information

Product Name	6,8-Difluoro-4-Pyridin-3-Yl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline
CAS No.	1139889-93-2
Molecular Formula	C21H16F2N2
Molecular Weight	334.36 g/mol
Synonyms	6,8-Difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline; 3H-Cyclopenta[c]quinoline, 6,8-difluoro-4-(3-pyridinyl)-3a,4,5,9b-tetrahydro-; 4-(3-Pyridinyl)-6,8-difluoro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline; Difluoropyridinyltetrahydrocyclopentaquinoline; CAS 1139889-93-2
EINECS	Contact for details

Quality Control

Our production of 6,8-Difluoro-4-Pyridin-3-Yl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.