Description

tert-Butyl 2,5-Diiodopyridin-3-Yl Carbonate is a high-value, multi-functional chemical intermediate featuring a protected carbonate group and halogenated pyridine core. This compound is essential for facilitating complex organic syntheses, particularly in the construction of advanced pharmaceutical scaffolds and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for its role in cross-coupling reactions and as a versatile building block.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysts and monomers for specialty polymers.
• Cross-Coupling Reactions: The diiodo-substituted pyridine ring makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new synthetic pathways.
• Ligand Preparation: Useful for synthesizing complex chelating agents and ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	tert-Butyl 2,5-Diiodopyridin-3-Yl Carbonate
CAS No.	1138444-30-0
Molecular Formula	C10H11I2NO3
Molecular Weight	462.99 g/mol
Synonyms	tert-Butyl 2,5-diiodopyridin-3-yl carbonate; 3-Pyridinol, 2,5-diiodo-, 1,1-dimethylethyl carbonate; 2,5-Diiodopyridin-3-yl tert-butyl carbonate; Carbonic acid, 2,5-diiodo-3-pyridinyl ester, 1,1-dimethylethyl ester; tert-Butyl (2,5-diiodopyridin-3-yl) carbonate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,5-Diiodopyridin-3-Yl Carbonate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.