Description

6-Bromo-2-Chloro-4-Iodopyridin-3-Amine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex heterocyclic scaffolds, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its halogenated pyridine core.
• Material Science: Serves as a building block for creating organic electronic materials, ligands for catalysis, and photoactive compounds.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions, leveraging the bromo and iodo substituents.
• Chemical Biology: Utilized in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	6-Bromo-2-Chloro-4-Iodopyridin-3-Amine
CAS No.	1138444-29-7
Molecular Formula	C5H3BrClIN2
Molecular Weight	332.35 g/mol
Synonyms	3-Amino-6-bromo-2-chloro-4-iodopyridine; 2-Chloro-6-bromo-4-iodopyridin-3-amine; 6-Bromo-2-chloro-4-iodo-3-pyridinamine; 4-Iodo-6-bromo-2-chloropyridin-3-amine; 3-Pyridinamine, 6-bromo-2-chloro-4-iodo-; 1138444-29-7; BCI Pyridine Derivative
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Chloro-4-Iodopyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.