Description

3-Methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid hydrochloride dihydrate is a high-purity, heterocyclic carboxylic acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules targeting various therapeutic and biological applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used as a building block for developing new active ingredients in crop protection and pest management solutions.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Material Science: Potential monomer or precursor for creating specialty polymers and advanced organic materials with specific electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and process development projects.

Basic Information

Product Name	3-Methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid hydrochloride dihydrate
CAS No.	1138444-24-2
Molecular Formula	C9H9N3O2 • HCl • 2H2O
Molecular Weight	263.68 g/mol (Monohydrate free base: 191.19)
Synonyms	6-Carboxy-3-methyl-3H-imidazo[4,5-b]pyridine hydrochloride dihydrate; 3-Methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid HCl salt dihydrate; 1-Methyl-1H-imidazo[4,5-b]pyridine-6-carboxylic acid hydrochloride dihydrate; Imidazo[4,5-b]pyridine-6-carboxylic acid, 3-methyl-, hydrochloride, dihydrate; 1138444-24-2; Building block for kinase inhibitors
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid hydrochloride dihydrate adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	12.0% - 15.0% (Theoretical for dihydrate: ~13.66%)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.