Description

tert-Butyl (4-Iodo-5-Methoxypyridin-3-Yl)-Methylcarbamate CAS NO 1138444-20-8 is a high-purity, advanced pharmaceutical intermediate featuring a functionalized pyridine core. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the multi-step manufacturing processes of Active Pharmaceutical Ingredients (APIs) requiring a halogenated, methoxy-substituted pyridine moiety.
• Chemical Biology Probes: Employed in the development of molecular probes and labeled compounds for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	tert-Butyl (4-Iodo-5-Methoxypyridin-3-Yl)-Methylcarbamate
CAS No.	1138444-20-8
Molecular Formula	C12H17IN2O3
Molecular Weight	364.18 g/mol
Synonyms	tert-Butyl N-[(4-Iodo-5-methoxy-3-pyridinyl)methyl]carbamate; 1,1-Dimethylethyl N-[(4-Iodo-5-methoxy-3-pyridinyl)methyl]carbamate; Carbamic acid, N-[(4-iodo-5-methoxy-3-pyridinyl)methyl]-, 1,1-dimethylethyl ester; BOC-Protected 4-Iodo-5-methoxy-3-pyridinemethylamine; 3-((tert-Butoxycarbonylamino)methyl)-4-iodo-5-methoxypyridine; (4-Iodo-5-methoxy-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Iodo-5-Methoxypyridin-3-Yl)-Methylcarbamate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring material that meets GMP-grade standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.