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6-Bromo-2-Chloro-3-Iodopyridine CAS NO 1138444-17-3


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CAS No.:1138444-17-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Bromo-2-Chloro-3-Iodopyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an invaluable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where precise functionalization is required.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
  • Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides by providing a versatile halogenated scaffold for further modification.
  • Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
  • Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of bromo and iodo substituents.
  • Ligand Synthesis: Utilized in the preparation of complex polydentate ligands for catalysis and metal-organic frameworks (MOFs).
  • Chemical Biology: Employed as a probe or tag in bioconjugation and the development of molecular imaging agents.

Basic Information

Item Details
Product Name 6-Bromo-2-Chloro-3-Iodopyridine
CAS No. 1138444-17-3
Molecular Formula C5H2BrClIN
Molecular Weight 318.34 g/mol
Synonyms 2-Chloro-6-bromo-3-iodopyridine; 3-Iodo-6-bromo-2-chloropyridine; 6-Bromo-2-chloro-3-iodopyridine; 2-Chloro-3-iodo-6-bromopyridine; Pyridine, 6-bromo-2-chloro-3-iodo-; 1138444-17-3; SCHEMBL21842427; BRN 12686151
EINECS Contact for details

Quality Control

Our 6-Bromo-2-Chloro-3-Iodopyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Heavy Metals < 10 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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