Description

tert-Butyl 2,6-Diiodopyridin-3-Yl Carbonate is a high-value, multi-functional chemical building block characterized by its reactive diiodopyridine core protected by a tert-butyl carbonate group. This compound is essential for advanced organic synthesis, particularly in pharmaceutical research and development, where it serves as a versatile precursor for constructing complex heterocyclic scaffolds. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its halogenated pyridine structure.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Material Science: Employed in the synthesis of organic electronic materials and liquid crystals, where the diiodo functionality allows for further functionalization.
• Chemical Biology & Proteomics: Utilized as a building block for synthesizing molecular probes and affinity tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise, multi-step functionalization of the pyridine ring.

Basic Information

Product Name	tert-Butyl 2,6-Diiodopyridin-3-Yl Carbonate
CAS No.	1138444-12-8
Molecular Formula	C10H11I2NO3
Molecular Weight	462.99 g/mol
Synonyms	tert-Butyl 2,6-Diiodo-3-pyridyl Carbonate; 3-[(tert-Butoxy)carbonyl]-2,6-diiodopyridine; 2,6-Diiodopyridin-3-yl tert-Butyl Carbonate; tert-Butyl Carbonate of 2,6-Diiodo-3-hydroxypyridine; 2,6-Diiodo-3-pyridinol tert-Butyl Carbonate; Boc-Protected 2,6-Diiodo-3-hydroxypyridine; 1138444-12-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,6-Diiodopyridin-3-Yl Carbonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for advanced intermediates, ensuring reliable supply for critical development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.