Description

3-Cyano-5-Methoxyisonicotinic Acid CAS NO 1138444-09-3 is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring both cyano and carboxylic acid functional groups on a methoxy-substituted pyridine ring, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Cyano-5-Methoxyisonicotinic Acid
CAS No.	1138444-09-3
Molecular Formula	C8H6N2O3
Molecular Weight	178.15 g/mol
Synonyms	5-Methoxy-3-cyanoisonicotinic acid; 5-Methoxy-3-cyanopyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 3-cyano-5-methoxy-; Isonicotinic acid, 3-cyano-5-methoxy-; 3-Cyano-5-methoxypyridine-4-carboxylic acid; 1138444-09-3; 3-Cyano-5-methoxy-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Cyano-5-Methoxyisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.