Description

4-Iodo-5-Methoxynicotinonitrile is a versatile halogenated pyridine derivative, a key building block in advanced organic synthesis. This compound is valued for its reactive iodine and nitrile functional groups, enabling precise chemical modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions to create diverse chemical libraries.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	4-Iodo-5-Methoxynicotinonitrile
CAS No.	1138444-07-1
Molecular Formula	C7H5IN2O
Molecular Weight	260.03 g/mol
Synonyms	5-Methoxy-4-iodonicotinonitrile; 4-Iodo-5-methoxy-3-pyridinecarbonitrile; 3-Cyano-5-methoxy-4-iodopyridine; Nicotinonitrile, 4-iodo-5-methoxy-; 1138444-07-1; 4-Iodo-5-methoxypyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Iodo-5-Methoxynicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.