Description

tert-Butyl (5-Bromo-3-Methoxypyridin-2-Yl)-Methylcarbamate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing new generation pesticides and herbicides with specific modes of action.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.
• Academic Research: Employed in university and institutional labs for methodological development and exploring new synthetic routes.

Basic Information

Product Name	tert-Butyl (5-Bromo-3-Methoxypyridin-2-Yl)-Methylcarbamate
CAS No.	1138443-96-5
Molecular Formula	C12H17BrN2O3
Molecular Weight	317.18 g/mol
Synonyms	tert-Butyl N-[(5-bromo-3-methoxypyridin-2-yl)methyl]carbamate; Carbamic acid, N-[(5-bromo-3-methoxy-2-pyridinyl)methyl]-, 1,1-dimethylethyl ester; Boc-Protected 5-Bromo-3-methoxy-2-pyridinemethylamine; 5-Bromo-3-methoxy-2-((((tert-butoxy)carbonyl)amino)methyl)pyridine; 2-(((tert-Butoxycarbonyl)amino)methyl)-5-bromo-3-methoxypyridine; N-Boc-5-Bromo-3-methoxy-2-aminomethylpyridine; Boc-Amino(5-bromo-3-methoxy-2-pyridyl)methane
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Bromo-3-Methoxypyridin-2-Yl)-Methylcarbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. We provide comprehensive analytical data including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.