Description

3-(Dimethoxymethyl)-5-Methoxy-4-(Trimethylsilyl)-Pyridine is a high-value, multi-functional pyridine derivative featuring both silyl and methoxymethyl protecting groups. This compound matters as a versatile and critical advanced pharmaceutical intermediate and organosilicon building block for complex organic synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those requiring silicon-containing or protected heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the pyridine core and silicon moiety offer unique biological activity.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as OLEDs or conductive polymers, due to its functionalized aromatic system.
• Organic Synthesis Building Block: The protected functional groups make it a valuable reagent for multi-step syntheses requiring selective deprotection strategies.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	3-(Dimethoxymethyl)-5-Methoxy-4-(Trimethylsilyl)-Pyridine
CAS No.	1138443-91-0
Molecular Formula	C13H23NO3Si
Molecular Weight	269.41 g/mol
Synonyms	4-(Trimethylsilyl)-5-methoxy-3-(dimethoxymethyl)pyridine; 5-Methoxy-4-(trimethylsilyl)-3-(dimethoxymethyl)pyridine; 3-(Dimethoxymethyl)-5-methoxy-4-(trimethylsilyl)pyridine; Pyridine, 3-(dimethoxymethyl)-5-methoxy-4-(trimethylsilyl)-; 1138443-91-0; TMS-protected pyridine derivative
EINECS	Contact for details

Quality Control

Our 3-(Dimethoxymethyl)-5-Methoxy-4-(Trimethylsilyl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place (recommended 2-8°C or as specified on the label) under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and easily oxidized nature. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.