Description

6-((tert-Butyldimethylsilyloxy)Methyl)-2,3-Dimethoxypyridine is a high-purity, protected pyridine derivative used as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials, where precise functional group manipulation is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing complex pyridine or piperidine cores.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific heterocyclic architectures.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and medicinal chemistry projects.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	6-((tert-Butyldimethylsilyloxy)Methyl)-2,3-Dimethoxypyridine
CAS No.	1138443-87-4
Molecular Formula	C14H25NO3Si
Molecular Weight	283.44 g/mol
Synonyms	2,3-Dimethoxy-6-(((tert-butyldimethylsilyl)oxy)methyl)pyridine; 6-(((tert-Butyldimethylsilyl)oxy)methyl)-2,3-dimethoxypyridine; 2,3-Dimethoxy-6-((TBDMS-oxy)methyl)pyridine; TBDMS-protected 2,3-dimethoxypyridinemethanol; (2,3-Dimethoxypyridin-6-yl)methoxy-tert-butyldimethylsilane; 6-(Hydroxymethyl)-2,3-dimethoxypyridine TBDMS ether; 6-(TBDMSOCH2)-2,3-Dimethoxypyridine
EINECS	Contact for details

Quality Control

Our 6-((tert-Butyldimethylsilyloxy)Methyl)-2,3-Dimethoxypyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to relevant quality management standards to support our global customer base in pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be stored away from direct light. Keep the container tightly sealed to minimize exposure to moisture and atmospheric contaminants. Store away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white solid or clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.