Description

3-Iodo-5-Methyl-1H-Pyrrolo[2,3-B]Pyridine is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily sought after by research scientists and process chemists in the pharmaceutical, biotechnology, and agrochemical industries for its utility in cross-coupling reactions and as a key scaffold in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small molecule drug candidates.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science: Serves as a building block for organic electronic materials and functional polymers.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions such as Suzuki, Sonogashira, and Buchwald-Hartwig aminations for C-C and C-N bond formation.
• Medicinal Chemistry Scaffold: Provides the core structure for library synthesis in high-throughput screening for new biological activities.
• Chemical Biology Probes: Used to create labeled compounds for studying biological pathways and protein interactions.

Basic Information

Product Name	3-Iodo-5-Methyl-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1138443-83-0
Molecular Formula	C8H7IN2
Molecular Weight	258.06 g/mol
Synonyms	5-Methyl-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-5-methyl-; 5-Methyl-3-iodo-7-azaindole; 3-Iodo-5-methyl-7-azaindole
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-Methyl-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.