Description

(2-Fluoro-Pyridin-3-Yl)-Hydrazine CAS NO 1138036-56-2 is a high-value fluorinated pyridine derivative and a versatile hydrazine-based building block. This compound is critical for the synthesis of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the fluorine atom and pyridine core enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Heterocyclic Chemistry Research: An essential building block for constructing complex nitrogen-containing heterocycles like pyrazoles, triazoles, and fused ring systems in medicinal chemistry.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers or organic electronic materials due to its reactive hydrazine group and aromatic system.

Basic Information

Product Name	(2-Fluoro-Pyridin-3-Yl)-Hydrazine
CAS No.	1138036-56-2
Molecular Formula	C5H6FN3
Molecular Weight	127.12 g/mol
Synonyms	2-Fluoro-3-hydrazinylpyridine; 3-Hydrazinyl-2-fluoropyridine; (2-Fluoropyridin-3-yl)hydrazine; 2-Fluoropyridine-3-ylhydrazine; 2-Fluoro-3-pyridinylhydrazine; 1138036-56-2; (2-Fluoro-3-pyridinyl)hydrazine
EINECS	Contact for details

Quality Control

Our (2-Fluoro-Pyridin-3-Yl)-Hydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.