Description

1-Methyl-5-(Piperidin-4-Yl)Pyridin-2(1H)-One Hydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant interest in modern organic synthesis. This compound matters for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. Pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers need this material for lead optimization, process development, and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead compound optimization within academic and industrial R&D laboratories.
• Process Chemistry Development: Serves as a standard or starting material for developing and scaling up robust, GMP-compliant synthetic routes.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying specific biological receptors or enzymes.
• Custom Synthesis Building Block: Employed by fine chemical suppliers for the custom manufacturing of specialized compounds and libraries.

Basic Information

Product Name	1-Methyl-5-(Piperidin-4-Yl)Pyridin-2(1H)-One Hydrochloride
CAS No.	1137950-65-2
Molecular Formula	C11H17ClN2O
Molecular Weight	228.72 g/mol
Synonyms	1-Methyl-5-(4-piperidinyl)-2(1H)-pyridinone hydrochloride; 5-(Piperidin-4-yl)-1-methylpyridin-2(1H)-one hydrochloride; 1-Methyl-5-piperidin-4-yl-1H-pyridin-2-one hydrochloride; 2(1H)-Pyridinone, 1-methyl-5-(4-piperidinyl)-, hydrochloride; 1-Methyl-5-(piperidin-4-yl)pyridin-2(1H)-one HCl; 1137950-65-2
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-(Piperidin-4-Yl)Pyridin-2(1H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and related substances to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.