Description

Ethyl 6-Phenylpiperidine-2-Carboxylate is a high-purity, synthetically valuable piperidine derivative used as a critical building block in advanced organic synthesis. This compound is essential for research and development in the pharmaceutical sector, where it serves as a key intermediate for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by fine chemical manufacturers, contract research organizations (CROs), and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new pharmacophores containing the piperidine scaffold.
• Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex esters, amides, and other functionalized piperidine derivatives.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Academic & Industrial R&D: Employed in methodological development and as a reference standard in analytical laboratories.

Basic Information

Product Name	Ethyl 6-Phenylpiperidine-2-Carboxylate
CAS No.	1137664-24-4
Molecular Formula	C14H19NO2
Molecular Weight	233.31 g/mol
Synonyms	Ethyl 6-phenyl-2-piperidinecarboxylate; 2-Piperidinecarboxylic acid, 6-phenyl-, ethyl ester; 6-Phenylpiperidine-2-carboxylic acid ethyl ester; Ethyl 6-phenylpipecolate; Ethyl 6-phenyl-2-piperidinecarboxylate; Ethyl 6-phenyl-2-piperidinecarboxylate (CAS 1137664-24-4)
EINECS	Contact for details

Quality Control

Our Ethyl 6-Phenylpiperidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.