Description

2-(4-Chloropyridin-2-Yl)-4,4-Dimethyl-4,5-Dihydrooxazole is a high-value, heterocyclic organic building block characterized by its fused oxazole and chloropyridine rings. This compound is critical for advanced organic synthesis, serving as a versatile precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a sophisticated scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for advanced organic materials, such as organic semiconductors or liquid crystals.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-(4-Chloropyridin-2-Yl)-4,4-Dimethyl-4,5-Dihydrooxazole
CAS No.	1137063-15-0
Molecular Formula	C10H11ClN2O
Molecular Weight	210.66 g/mol
Synonyms	4,4-Dimethyl-2-(4-chloro-2-pyridinyl)-4,5-dihydrooxazole; 2-(4-Chloropyridin-2-yl)-4,4-dimethyl-4,5-dihydrooxazole; 4,5-Dihydro-4,4-dimethyl-2-(4-chloro-2-pyridinyl)oxazole; 2-(4-Chloro-2-pyridinyl)-4,4-dimethyl-2-oxazoline; 4,4-Dimethyl-2-(4-chloropyridin-2-yl)-4,5-dihydrooxazole; 2-(4-Chloro-2-pyridyl)-4,4-dimethyl-4,5-dihydrooxazole
EINECS	Contact for details

Quality Control

Our 2-(4-Chloropyridin-2-Yl)-4,4-Dimethyl-4,5-Dihydrooxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.