Description

2-Amino-2-[4-(2-Pyridyl)Phenyl]Acetic Acid Hydrochloride is a high-purity, non-natural amino acid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs).
• Peptidomimetics & Drug Discovery: Used in the design and synthesis of peptide analogs and other bioactive compounds targeting specific receptors.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Chemical Biology Research: Employed in the study of enzyme mechanisms and protein-protein interactions as a modified amino acid probe.
• Academic & Industrial R&D: Essential for synthetic chemistry research in universities and corporate laboratories focusing on heterocyclic and amino acid chemistry.

Basic Information

Product Name	2-Amino-2-[4-(2-Pyridyl)Phenyl]Acetic Acid Hydrochloride
CAS No.	1135818-89-1
Molecular Formula	C₁₃H₁₂N₂O₂·HCl
Molecular Weight	264.71 g/mol (Free base: 228.25 g/mol)
Synonyms	2-Amino-2-(4-(pyridin-2-yl)phenyl)acetic acid hydrochloride; (4-(2-Pyridyl)phenyl)glycine hydrochloride; 2-(4-(2-Pyridyl)phenyl)glycine HCl; α-Amino[4-(2-pyridinyl)phenyl]acetic acid hydrochloride; 2-Amino-2-(4-(2-pyridinyl)phenyl)ethanoic acid hydrochloride; 4-(2-Pyridyl)phenylglycine hydrochloride; (R/S)-2-Amino-2-(4-(pyridin-2-yl)phenyl)acetic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-[4-(2-Pyridyl)Phenyl]Acetic Acid Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.