Description

1-[(6-Chloro-3-Pyridinyl)Methyl]Piperazine(Saltdata: 2Hcl) is a high-purity, advanced pharmaceutical intermediate with a defined dihydrochloride salt form. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the agrochemical and pharmaceutical sectors. Industrial and R&D chemists need this material for developing next-generation products, where precise chemical structure and salt form are essential for efficacy and process scalability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial precursor for developing modern insecticides and pesticides, leveraging the bioactive chloronicotinyl moiety.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new chemical entities and reaction pathways in heterocyclic chemistry.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for metal catalysis and coordination chemistry applications.
• Fine Chemical Manufacturing: Integrated into multi-step synthesis processes for producing high-value, specialty chemicals with specific functional group requirements.

Basic Information

Product Name	1-[(6-Chloro-3-Pyridinyl)Methyl]Piperazine(Saltdata: 2Hcl)
CAS No.	1135439-04-1
Molecular Formula	C10H15Cl2N3 • 2HCl
Molecular Weight	312.08 g/mol (Free base: 213.12 g/mol)
Synonyms	1-[(6-Chloro-3-pyridyl)methyl]piperazine dihydrochloride; (6-Chloro-3-pyridinyl)methylpiperazine dihydrochloride; 1-((6-Chloropyridin-3-yl)methyl)piperazine dihydrochloride; 1-[(6-Chloro-3-pyridinyl)methyl]piperazine hydrochloride (1:2); Piperazine, 1-[(6-chloro-3-pyridinyl)methyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-[(6-Chloro-3-Pyridinyl)Methyl]Piperazine dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.