Description

1-Methyl-5-Nitro-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyrrolopyridine heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the generation of compound libraries for high-throughput screening.
• Kinase Inhibitor Development: Its structural motif is highly relevant for the design and synthesis of potential kinase inhibitors, a major class of targeted cancer therapies.
• Agrochemical Research: Used in the research and development of new agrochemicals, such as herbicides and pesticides, leveraging its heterocyclic core.
• Material Science: Investigated as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient nitro-substituted aromatic system.

Basic Information

Product Name	1-Methyl-5-Nitro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1135437-92-1
Molecular Formula	C9H7N3O2
Molecular Weight	189.17 g/mol
Synonyms	1-Methyl-5-nitropyrrolo[2,3-b]pyridine; 5-Nitro-1-methyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 1-methyl-5-nitro-; Pyrrolo[2,3-b]pyridine, 1-methyl-5-nitro-
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-Nitro-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.