Description

tert-Butyl 4-(3-Cyano-6-Cyclopropyl-2-Pyridinyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-value, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly for research and development of new chemical entities.
• API Synthesis: Used in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) targeting specific biological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Chemical Reference Standard: Can be used as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	tert-Butyl 4-(3-Cyano-6-Cyclopropyl-2-Pyridinyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	1135283-84-9
Molecular Formula	C18H24N4O2
Molecular Weight	328.41 g/mol
Synonyms	1-Boc-4-(3-cyano-6-cyclopropylpyridin-2-yl)piperazine; tert-Butyl 4-(3-cyano-6-cyclopropylpyridin-2-yl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(3-cyano-6-cyclopropyl-2-pyridinyl)piperazine; 2-(1-Boc-piperazin-4-yl)-6-cyclopropylnicotinonitrile; BOC-4-(3-Cyano-6-Cyclopropyl-2-Pyridinyl)Piperazine; 1135283-84-9; tert-Butyl 4-(3-cyano-6-cyclopropyl-2-pyridyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Cyano-6-Cyclopropyl-2-Pyridinyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and compliance documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.