Description

Methyl 3-Amino-6-Cyclopropylthieno[2,3-B]Pyridine-2-Carboxylate is a high-value, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique fused-ring structure containing thiophene and pyridine moieties makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides with specific activity profiles.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential application in the synthesis of organic electronic materials due to its conjugated heterocyclic system.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Methyl 3-Amino-6-Cyclopropylthieno[2,3-B]Pyridine-2-Carboxylate
CAS No.	1135283-79-2
Molecular Formula	C12H12N2O2S
Molecular Weight	248.30 g/mol
Synonyms	Methyl 3-amino-6-cyclopropylthieno[2,3-b]pyridine-2-carboxylate; 3-Amino-6-cyclopropylthieno[2,3-b]pyridine-2-carboxylic acid methyl ester; 1135283-79-2; Thieno[2,3-b]pyridine-2-carboxylic acid, 3-amino-6-cyclopropyl-, methyl ester; Methyl 3-amino-6-cyclopropylthieno[2,3-b]pyridinyl-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-6-Cyclopropylthieno[2,3-B]Pyridine-2-Carboxylate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.