Description

6-Cyclopropyl-1-Methyl-1H-Pyrazolo[3,4-B]Pyridin-3-Ylamine is a high-purity, advanced pharmaceutical intermediate with a distinct pyrazolopyridine core structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Serves as a core scaffold for the research and production of small molecule kinase inhibitors, a major class of oncology therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring the pyrazolopyridine moiety.
• Biochemical Tool Compound: Utilized in biochemical assays and as a reference standard for pharmacological studies.
• Custom Synthesis Building Block: Supplied to contract research organizations (CROs) and custom synthesis facilities for client-specific molecule construction.

Basic Information

Product Name	6-Cyclopropyl-1-Methyl-1H-Pyrazolo[3,4-B]Pyridin-3-Ylamine
CAS No.	1135283-77-0
Molecular Formula	C10H12N4
Molecular Weight	188.23 g/mol
Synonyms	3-Amino-6-cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine; 6-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine; 1-Methyl-6-cyclopropyl-1H-pyrazolo[3,4-b]pyridin-3-amine; Pyrazolo[3,4-b]pyridin-3-amine, 6-cyclopropyl-1-methyl-; 1135283-77-0; 6-Cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-3-ylamine
EINECS	Contact for details

Quality Control

Our 6-Cyclopropyl-1-Methyl-1H-Pyrazolo[3,4-B]Pyridin-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.