Description

5-Bromo-6-Cyclopropyl-2-Hydroxynicotinonitrile is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromo, cyano, and hydroxypyridine functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Building block for developing new herbicides and fungicides with novel modes of action.
• Material Science: Used in the creation of specialized ligands for catalysis and functional organic materials.
• Chemical Biology: Probe or linker molecule in the study of biological pathways and target identification.
• Custom Synthesis: Serves as a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	5-Bromo-6-Cyclopropyl-2-Hydroxynicotinonitrile
CAS No.	1135283-57-6
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	2-Hydroxy-5-bromo-6-cyclopropylnicotinonitrile; 5-Bromo-6-cyclopropyl-2-hydroxypyridine-3-carbonitrile; 3-Cyano-5-bromo-6-cyclopropyl-2-pyridinol; 5-Bromo-6-cyclopropyl-2-oxo-1,2-dihydropyridine-3-carbonitrile; 2-Pyridinol, 5-bromo-6-cyclopropyl-3-cyano-; 1135283-57-6; 5-Br-6-Cyclopropyl-2-OH-nicotinonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Cyclopropyl-2-Hydroxynicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.