Description

5-Bromo-2-Chloro-6-Methyl-4-(Trifluoromethyl)Nicotinonitrile is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its complex halogenated and trifluoromethylated pyridine core makes it a critical intermediate for developing novel active compounds. This product is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridine structure.
• Material Science Research: Serves as a precursor for synthesizing specialized ligands, organic semiconductors, and functional polymers.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis of complex target molecules.

Basic Information

Product Name	5-Bromo-2-Chloro-6-Methyl-4-(Trifluoromethyl)Nicotinonitrile
CAS No.	1135283-49-6
Molecular Formula	C9H3BrClF3N2
Molecular Weight	299.48 g/mol
Synonyms	5-Bromo-2-chloro-6-methyl-4-(trifluoromethyl)pyridine-3-carbonitrile; 3-Cyano-5-bromo-2-chloro-6-methyl-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-5-bromo-2-chloro-6-methylnicotinonitrile; 5-Bromo-2-chloro-4-(trifluoromethyl)-6-picolinonitrile; 1135283-49-6; 5-Br-2-Cl-6-Me-4-CF3-Pyridine-3-CN
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-6-Methyl-4-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if possible. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.