Description

3-Bromo-6-Chloro-2,2'-Bipyridine-5-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique halogenated and nitrile-substituted bipyridine scaffold, which provides multiple reactive sites for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, ligand synthesis, and materials science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Ligand Synthesis: Serves as a versatile starting material for constructing sophisticated chelating ligands used in catalysis and coordination chemistry.
• Agrochemical Research: Employed in the development of novel herbicides and fungicides, leveraging its halogenated heterocyclic structure.
• Material Science Building Block: Used in the creation of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to its bromo and chloro substituents.

Basic Information

Item	Detail
Product Name	3-Bromo-6-Chloro-2,2'-Bipyridine-5-Carbonitrile
CAS No.	1135283-47-4
Molecular Formula	C11H5BrClN3
Molecular Weight	294.53 g/mol
Synonyms	3-Bromo-6-chloro-2,2'-bipyridine-5-carbonitrile; 5-Cyano-3-bromo-6-chloro-2,2'-bipyridine; 2,2'-Bipyridine-5-carbonitrile, 3-bromo-6-chloro-; 3-Bromo-6-chloro-5-cyano-2,2'-bipyridine; 6-Chloro-3-bromo-2,2'-bipyridine-5-carbonitrile; Bipyridine-5-carbonitrile, 3-bromo-6-chloro-2,2'-
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Chloro-2,2'-Bipyridine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are available upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.