Description

Ethyl 3-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-2-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters because its unique imidazopyridine core, combined with chloro and trifluoromethyl substituents, provides a versatile scaffold for creating novel molecules with tailored properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) or charge-transport materials.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Institutional Research: Utilized in university and institutional labs for methodological development in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	Ethyl 3-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-2-Carboxylate
CAS No.	1135283-40-7
Molecular Formula	C11H8ClF3N2O2
Molecular Weight	292.64 g/mol
Synonyms	Ethyl 3-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate; 2-Imidazo[1,2-a]pyridinecarboxylic acid, 3-chloro-6-(trifluoromethyl)-, ethyl ester; 1135283-40-7; Ethyl 3-chloro-6-trifluoromethylimidazo[1,2-a]pyridine-2-carboxylate; Imidazo[1,2-a]pyridine-2-carboxylic acid, 3-chloro-6-(trifluoromethyl)-, ethyl ester; 3-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.