Description

6-Hydroxy-5-Iodonicotinonitrile is a versatile halogenated pyridine derivative, a key heterocyclic building block prized for its unique reactivity profile. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the iodine moiety for further functionalization.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the construction of organic electronic materials and metal-organic frameworks (MOFs) due to its functional groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	6-Hydroxy-5-Iodonicotinonitrile
CAS No.	1135283-36-1
Molecular Formula	C6H3IN2O
Molecular Weight	245.00 g/mol
Synonyms	5-Iodo-6-hydroxynicotinonitrile; 6-Hydroxy-5-iodo-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 6-hydroxy-5-iodo-; 5-Iodo-6-oxo-1,6-dihydropyridine-3-carbonitrile; 5-Iodo-6-hydroxypyridine-3-carbonitrile; 6-Hydroxy-5-iodopyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-5-Iodonicotinonitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full analytical data are provided for every shipment, ensuring traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.