Description

5-Bromo-6-Cyclopropyl-1-Methyl-1H-Pyrazolo[3,4-B]Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, offering researchers precise molecular control. It is primarily needed by R&D teams and process chemists in the pharmaceutical, biotechnology, and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the research and development of new drug candidates, particularly in oncology and antiviral therapies.
• Kinase Inhibitor Synthesis: A key precursor in the synthesis of small molecule kinase inhibitors due to its pyrazolopyridine core.
• Agrochemical Research: Used in the discovery and development of new generation pesticides and herbicides.
• Chemical Biology Probe Development: Employed in creating molecular tools for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for scale-up and production under cGMP conditions for clinical trial materials.
• Academic & Institutional Research: Utilized in universities and research institutes for exploratory synthetic chemistry and medicinal chemistry programs.

Basic Information

Product Name	5-Bromo-6-Cyclopropyl-1-Methyl-1H-Pyrazolo[3,4-B]Pyridin-3-Amine
CAS No.	1135283-06-5
Molecular Formula	C10H11BrN4
Molecular Weight	267.13 g/mol
Synonyms	5-Bromo-6-cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine; 1H-Pyrazolo[3,4-b]pyridin-3-amine, 5-bromo-6-cyclopropyl-1-methyl-; 1135283-06-5; 5-Bromo-6-cyclopropyl-1-methylpyrazolo[3,4-b]pyridin-3-amine; 5-Bromo-6-cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-3-amine
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Cyclopropyl-1-Methyl-1H-Pyrazolo[3,4-B]Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.