Description

5-[Amino(Hydroxyimino)Methyl]-n-Hydroxy-2-Pyridinecarboxamide is a specialized pyridine derivative with a unique bifunctional hydroxamic acid and amidoxime structure, making it a valuable intermediate for advanced chemical synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the design of metal-chelating agents and enzyme inhibitors. It serves the needs of pharmaceutical R&D laboratories, agrochemical innovators, and manufacturers of high-purity fine chemicals seeking to develop novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting metalloenzymes like histone deacetylases (HDACs) or matrix metalloproteinases (MMPs).
• Chelating Agent Precursor: Used to develop high-affinity chelators for metal ions (e.g., Fe³⁺, Zn²⁺, Cu²⁺) with applications in analytical chemistry, water treatment, and radiopharmaceuticals.
• Agrochemical Research: Serves as an intermediate in creating new fungicides or herbicides that act by disrupting metal-dependent processes in pests.
• Chemical Biology Probe Development: Utilized in academic and industrial research to create activity-based probes for studying enzyme function and inhibition.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce hydroxamic acid and amidoxime functional groups into complex molecules.

Basic Information

Product Name	5-[Amino(Hydroxyimino)Methyl]-n-Hydroxy-2-Pyridinecarboxamide
CAS No.	1135282-99-3
Molecular Formula	C8H10N4O3
Molecular Weight	210.19 g/mol
Synonyms	5-(Amino(hydroxyimino)methyl)-N-hydroxy-2-pyridinecarboxamide; 2-Pyridinecarboxamide, 5-[amino(hydroxyimino)methyl]-N-hydroxy-; N-Hydroxy-5-(amino(hydroxyimino)methyl)picolinamide; 5-(Amino-C,N-dihydroxyiminomethyl)-2-pyridinecarbohydroxamic acid; Picolinamide, N-hydroxy-5-(amino(hydroxyimino)methyl)-; 5-Carbamoylpyridine-2-hydroxamic acid amidoxime; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 5-[Amino(Hydroxyimino)Methyl]-n-Hydroxy-2-Pyridinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Specifications can be developed to meet research-grade or GMP intermediate requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.