Description

2-Bromo-6-(trifluoromethyl)imidazo[1,2-a]pyridine is a high-value, multi-functional heterocyclic building block of significant interest in modern synthetic chemistry. Its core value lies in the strategic combination of a reactive bromine substituent and a stable, electron-withdrawing trifluoromethyl group on the imidazopyridine scaffold, enabling precise molecular diversification. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
• Agrochemical Research: Used to construct novel heterocyclic scaffolds for developing new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions for carbon-carbon and carbon-nitrogen bond formation.
• Functional Group Transformation: The reactive site allows for further derivatization to introduce amines, ethers, or other functional groups, expanding chemical space.

Basic Information

Product Name	2-Bromo-6-(trifluoromethyl)imidazo[1,2-a]pyridine
CAS No.	1135282-92-6
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.03 g/mol
Synonyms	2-Bromo-6-(trifluoromethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 2-bromo-6-(trifluoromethyl)-; 2-Bromo-6-trifluoromethylimidazo[1,2-a]pyridine; 1135282-92-6; 2-Bromo-6-(trifluoromethyl)-imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(trifluoromethyl)imidazo[1,2-a]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.